Calreticulin anticorps (AA 367-417)

N° du produit ABIN7451672

L’anticorps Lapin Polyclonal anti-Calreticulin a été validé pour WB et IP. Il convient pour détecter Calreticulin dans des échantillons de Humain et Souris.

Aperçu rapide pour Calreticulin anticorps (AA 367-417) (ABIN7451672)

Antigène: Calreticulin (CALR)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calreticulin est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-Calreticulin anticorps

Épitope: AA 367-417

Fonction: Rabbit anti-Calreticulin Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 367 and 417

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Calreticulin

Antigène: Calreticulin (CALR)

Autre désignation: Calreticulin

Sujet: Background: Calreticulin is identified as a multifunctional protein that acts as a lectin chaperone and calcium binding protein. Calreticulin is found in the lumen of the endoplasmic reticulum and nucleus. In the nucleus, Calreticulin appears to function as a coregulator of nuclear hormone receptors. Increased autoantibody titers against calreticulin are associated with systemic lupus.

ID gène: 811

NCBI Accession: NP_004334

UniProt: P27797

Pathways: Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response